Therefore, for diseases located in the upper thoracic region, including cervical region, radiotherapy is an efficient treatment selection. Surgery operation has not been an appropriate treatment for those with locally advanced tumors because it was difficult to achieve a clear margin. Upper thoracic esophageal carcinoma (UTEC) occurs rarely and accounts for only 5%-10% of all esophageal carcinomas in PR.China. ConclusionsĬomparing to the sMLC, the mMLC not only demonstrated higher efficiencies and more optimal target coverage, but also considerably improved the dose sparing of OARs in the IMRT planning for UTEC. Also, compared to plans with the sMLC, the plans with the mMLC showed advantages in dose coverage of the planning gross tumor volume (Pgtv) (CI 0.706 ± 0.056/HI 1.093 ± 0.021) and the planning target volume (PTV) (CI 0.707 ± 0.029/HI 1.315 ± 0.013) ( p < 0.05). The IMRT plans with the mMLC were more efficient (average MUs: 703.1 ± 68.3) than plans with the sMLC (average MUs: 833.4 ± 73.8) ( p < 0.05).
The monitor unites (MUs) and dose volume histogram-based parameters were compared between the IMRT plans with sMLC and with mMLC.
Methods and materialsġ0 patients with UTEC were retrospectively planned with the sMLC and the mMLC. To study the impacts of multileaf collimators (MLC) width in the intensity-modulated radiotherapy (IMRT) planning for the upper thoracic esophageal cancer (UTEC).
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